By Graca Soveral, Soren Nielsen, Angela Casini
Since the invention of Aquaporin-1 (AQP1) as a water channel, many reviews have published the significance of aquaporins in mammalian body structure and pathophysiology in addition to plant and microbial biology. The experiences have additionally proven aquaporins as strength drug goals and objectives for making improvements to crop properties.
Written through a global staff of individuals on the vanguard of the sector, Aquaporins in overall healthiness and illness: New Molecular goals for Drug Discovery offers the most recent examine advances in aquaporins and different significant intrinsic protein (MIP) channels. the 1st component to the ebook describes the final suggestions of aquaporin channel functionality, genomic study, structure-function research of aquaporins and glycerol facilitators, and law via gating and trafficking, together with yeast aquaporin legislation and serve as. the second one part discusses the physiological and pathophysiological roles of aquaporins in people and microbes. the ultimate part covers the improvement of inhibitors of aquaporin functionality. The book’s epilogue bargains destiny views and instructions, regularly within the region of aquaporin-based diagnostics and therapeutics.
Stimulating destiny examine in this vital protein family members, this publication allows a paradigm shift within the figuring out and roles of aquaporin membrane proteins in all organic settings. It encourages scientists to strengthen novel ways for the therapy of human ailments in response to aquaporin functionality or dysfunction.
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Extra info for Aquaporins in Health and Disease
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Aquaporins in Health and Disease by Graca Soveral, Soren Nielsen, Angela Casini