By Alison Campbell, Simon Fishel
Unlike traditional unmarried day-by-day observations, time lapse expertise presents hundreds and hundreds of pictures, which permits pinpointing of key occasions within the embryo’s in vitro improvement in addition to the detection of short yet major severe adjustments. this knowledge is useful in opting for the main workable embryos from a cohort and raises the possibilities of a good outcome.
The Atlas of Time Lapse Embryology describes intimately the know-how and methods surrounding time lapse embryology. The publication additionally covers the medical features of time lapse imaging, morphokinetic timings, implantation facts, fertilization, compaction, blastulation, abnormal cleavages, multinucleation, vacuolation, zona defects, and different issues.
The ebook is straightforward to learn, functional, and illustrated with dozens of pictures and videos to assist clarify various thoughts. it is going to support practitioners to raised know the way time lapse tracking may perhaps dramatically bring up flexibility within the IVF health facility, and most significantly, increase medical results.
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Additional info for Atlas of Time Lapse Embryology
Fertil Steril. 2013;99:1030–1034. 18. Sathananthan AH, Ratnam SS, Ng SC, et al. The sperm centriole: its inheritance, replication and perpetuation in early human embryos. Hum Reprod. 1996;11(2):345–356. 7 Clinical Results: Dynamic Aspects – Fragmentation Sue Montgomery Fragmentation is a common feature of human embryo cleavage stage development in clinical in vitro fertilization (IVF) programmes, but its etiology is poorly understood. 1 Fragmentation usually arises at the first cleavage division.
10 Blastulation Sue Montgomery Blastulation is the process leading to the formation of a blastocoel, where the cells on the outside of the embryo polarize to form the trophectoderm (TE), creating an impermeable seal. Fluid is then transported to the extracellular spaces on the interior of the embryo, via sodium transport channels, causing blastocyst expansion. Tight junctions formed in the process of compaction prevent the leakage of fluid from the cavity. The inner cell mass (ICM) also becomes defined within the cavity.
Garello, Baker H, Rai J, Montgomery S, et al. Pronuclear orientation, polar body placement, and embryo quality after intracytoplasmic sperm injection and in-vitro fertilization: further evidence for polarity in human oocytes? Hum Reprod. 1999;14:2588–2595. 5. Cooke S, Tyler JP, Driscoll GL. Meiotic spindle location and identification and its effect on embryonic cleavage plane and early development. Hum Reprod. 2003;18:2397–2405. Hardarson T, Lundin K, Hamberger L. The position of the metaphase II spindle cannot be predicted by the location of the first polar body in the human oocyte.
Atlas of Time Lapse Embryology by Alison Campbell, Simon Fishel